Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475184 | 0.80 | ALDH1A1 (0.36) | ALDH1A1POLBKMT2ASMN1; SMN2KDM5B | |
| SCHEMBL1476343 | 0.79 | KDM5B (0.33) | ALDH1A1POLBKMT2ASMN1; SMN2KDM5B | |
| SCHEMBL31413853 | 0.77 | ALDH1A1 (0.36) | ALDH1A1POLBKMT2ASMN1; SMN2KDM5B | |
| SCHEMBL18485074 | 0.76 | KDM5B (0.38) | ALDH1A1POLBKDM5BCYP4F2CYP4A11 | |
| SCHEMBL25251923 | 0.76 | CD274 (0.38) | KMT2ACYP4F2CYP4A11 | |
| SCHEMBL20519004 | 0.75 | CYP4F2 (0.35) | CYP2C19CYP4F2CYP4A11RET | |
| SCHEMBL31413839 | 0.74 | ALDH1A1 (0.34) | ALDH1A1POLBKMT2ASMN1; SMN2KDM5B | |
| SCHEMBL14903851 | 0.73 | KMT2A (0.38) | ALDH1A1POLBKMT2ASMN1; SMN2KDM5B | |
| SCHEMBL14653527 | 0.71 | CYP4F2 (0.42) | ALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL22235919 | 0.71 | ALDH1A1 (0.38) | ALDH1A1POLBKMT2ASMN1; SMN2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025078984-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AS KRAS DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-04-17 | — | — | WO | disclosed |