Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.45 |
| ▸ | GRM5 | P41594 | 5/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31414517 | 0.89 | PDK4 (0.56) | CNR1PDK4JAK1NAMPTSCN9A | |
| SCHEMBL14143340 | 0.79 | PDK4 (0.61) | CNR1PDK4JAK1NAMPTHTR6 | |
| SCHEMBL4096970 | 0.77 | NAMPT (0.57) | PDK4JAK1NAMPTSCN9AHTR6 | |
| SCHEMBL6847847 | 0.76 | PDK4 (0.69) | CNR1PDK4JAK1NAMPTSCN9A | |
| SCHEMBL19284578 | 0.76 | PDK4 (0.65) | CNR1PDK4JAK1NAMPTSCN9A | |
| SCHEMBL31414515 | 0.76 | SCN9A (0.45) | JAK1NAMPTSCN9A | |
| SCHEMBL29115508 | 0.75 | SCN9A (0.51) | PDK4JAK1NAMPTSCN9AHTR6 | |
| SCHEMBL19284668 | 0.75 | PDK4 (0.61) | CNR1PDK4JAK1NAMPTSCN9A | |
| SCHEMBL19284633 | 0.75 | PDK4 (0.61) | CNR1PDK4JAK1NAMPTSCN9A | |
| SCHEMBL25338940 | 0.75 | PDK4 (0.60) | CNR1PDK4JAK1NAMPTSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735422-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | Sanofi (FR) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006827-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | GENZYME CORPORATION (US) | 2025-01-02 | — | — | WO | disclosed |