Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6122855 | 1.00 | CYP2A6 (0.49) | CYP2A6CSNK2A1NOS3NOS1NOS2 | |
| SCHEMBL1569635 | 0.84 | CYP2A6 (0.49) | CYP2A6CSNK2A1IDO1MAPTLMNA | |
| SCHEMBL11339655 | 0.81 | CYP2A6 (0.53) | CYP2A6CSNK2A1NOS3NOS1NOS2 | |
| SCHEMBL28018344 | 0.80 | NOS3 (0.39) | CYP2A6NOS3NOS1NOS2IDO1 | |
| SCHEMBL30453664 | 0.79 | CYP2A6 (0.51) | CYP2A6CSNK2A1IDO1MAPTLMNA | |
| SCHEMBL28856582 | 0.79 | CSNK2A1 (0.51) | CYP2A6CSNK2A1NOS3NOS1NOS2 | |
| SCHEMBL2581205 | 0.79 | CYP2A6 (0.51) | CYP2A6CSNK2A1IDO1MAPTLMNA | |
| SCHEMBL836823 | 0.78 | CYP2A6 (0.50) | CYP2A6CSNK2A1IDO1MAPTLMNA | |
| SCHEMBL2560634 | 0.76 | NOS3 (0.44) | CYP2A6NOS3NOS1NOS2IDO1 | |
| SCHEMBL7024324 | 0.76 | HIF1A (0.54) | NOS3NOS1NOS2IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747251-A1 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025125688-A2 | NOVEL COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025019479-A1 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |