Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.56 |
| ▸ | TNF | P01375 | 4/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.56 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | IL1B | P01584 | 1/20 | 0.56 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20913604 | 1.00 | CRBN (0.56) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL19453154 | 0.95 | CRBN (0.58) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL21069441 | 0.91 | CRBN (0.52) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL20819237 | 0.89 | CRBN (0.59) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL25036210 | 0.89 | CRBN (0.54) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL25036780 | 0.88 | CRBN (0.57) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL19453157 | 0.86 | CRBN (0.59) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL20819230 | 0.85 | CRBN (0.60) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL29424175 | 0.85 | CRBN (0.60) | CRBNIKZF3TNFDDB1IKZF1 | |
| SCHEMBL25031815 | 0.84 | TNF (0.53) | CRBNIKZF3TNFDDB1IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054181-A1 | TARGETED DEGRADER MOLECULES AND LIGAND DRUG CONJUGATES THEREOF | SEAGEN INC. (US) | 2025-03-13 | — | — | WO | disclosed |