Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415789 | 0.96 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL31415764 | 0.91 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL31415759 | 0.84 | CYP19A1 (0.64) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL31415786 | 0.84 | CYP19A1 (0.56) | CYP11B1CYP11B2CYP19A1TBXAS1HRH4 | |
| SCHEMBL31415791 | 0.79 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1TBXAS1HRH4 | |
| SCHEMBL31415761 | 0.79 | CYP19A1 (0.58) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL31415754 | 0.79 | CYP19A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL31415760 | 0.79 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1TBXAS1QPCT | |
| SCHEMBL31415772 | 0.79 | CYP19A1 (0.57) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL31415758 | 0.79 | CYP19A1 (0.52) | CYP19A1MAPTHRH4HRH3EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | claimed |
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | disclosed |