Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.62 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415787 | 0.87 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL31415764 | 0.82 | CYP11B1 (0.55) | CYP19A1GBA1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL31415759 | 0.80 | CYP19A1 (0.64) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL31415789 | 0.80 | CYP11B1 (0.52) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL31415749 | 0.79 | CYP11B1 (0.51) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL31415746 | 0.79 | TBXAS1 (0.63) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL31415777 | 0.79 | CYP19A1 (0.52) | CYP19A1GBA1BCHEMAPTHRH4 | |
| SCHEMBL5303970 | 0.78 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL31415747 | 0.77 | GBA1 (0.52) | CYP19A1GBA1BCHEHRH4 | |
| SCHEMBL31415833 | 0.74 | TBXAS1 (0.46) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | claimed |
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | disclosed |