Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415761 | 0.87 | CYP19A1 (0.58) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL31415791 | 0.82 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL31415760 | 0.82 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL31415772 | 0.82 | CYP19A1 (0.57) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31415764 | 0.82 | CYP11B1 (0.55) | CYP1A2CYP3A4CYP2D6CYP11B1CYP11B2 | |
| SCHEMBL31415788 | 0.80 | HRH4 (0.45) | CYP1A2CYP2D6CYP19A1HRH4NR1I3 | |
| SCHEMBL31415786 | 0.80 | CYP19A1 (0.56) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL31415832 | 0.79 | HMOX1 (0.54) | CYP11B1CYP11B2CYP19A1HRH4 | |
| SCHEMBL31415790 | 0.79 | HRH4 (0.43) | CYP1A2CYP2D6CYP19A1HRH4NR1I3 | |
| SCHEMBL27944073 | 0.77 | CYP11B1 (0.69) | CYP1A2CYP3A4CYP2D6CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | claimed |
| WO-2025003984-A1 | INHIBITORS OF HEME OXYGENASE, COMPOSITIONS AND USES THEREOF | Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) | 2025-01-02 | — | — | WO | disclosed |