SCHEMBL31416634

SCHEMBL31416634

Cc1nc(C(F)(F)F)ncc1S(=O)(=O)N1CC2(CN(C3CC4(COC4)C3)C2)C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33
PIK3CD O00329 1/20 0.31
PIK3CG P48736 1/20 0.31
CYP11B2 P19099 1/20 0.31
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27034099 0.96 ALOX5AP (0.35) ALOX5APFEN1PIK3CDPIK3CGOPRM1
SCHEMBL30845924 0.96 ALOX5AP (0.35) ALOX5APFEN1PIK3CDPIK3CGOPRM1
SCHEMBL31416641 0.94 ALOX5AP (0.33) ALOX5APFEN1CYP11B2
SCHEMBL30719521 0.89 HCRTR1 (0.32) CYP11B2
SCHEMBL31416568 0.87 ALOX5AP (0.32) ALOX5APFEN1
SCHEMBL31416521 0.87 LRRK2 (0.34) OPRM1OPRL1
SCHEMBL27034210 0.87 ALOX5AP (0.33) ALOX5APFEN1OPRM1OPRL1
SCHEMBL30845913 0.86 ALOX5AP (0.33) ALOX5APFEN1OPRM1OPRL1
SCHEMBL27034112 0.86 ALOX5AP (0.33) ALOX5APFEN1OPRM1OPRL1
SCHEMBL31416687 0.85 OPRM1 (0.34) ALOX5APFEN1OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043148-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2025-02-27 WO claimed
WO-2025043148-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2025-02-27 WO disclosed