Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MARS1 | P56192 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31283369 | 0.85 | KMT2A (0.37) | NPC1L3MBTL1MAPTDGAT1ALDH1A1 | |
| SCHEMBL25318502 | 0.83 | NPC1 (0.39) | NPC1PTGER1DGAT1F2RL1 | |
| SCHEMBL31283281 | 0.77 | DGAT1 (0.33) | NPC1DGAT1 | |
| SCHEMBL20489156 | 0.77 | DGAT1 (0.34) | NPC1LMNAMAPTDGAT1KDM4E | |
| SCHEMBL28746975 | 0.76 | DGAT1 (0.34) | NPC1DGAT1 | |
| SCHEMBL28586944 | 0.76 | DGAT1 (0.38) | NPC1DGAT1 | |
| SCHEMBL31283560 | 0.73 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL15051452 | 0.73 | NPC1 (0.48) | NPC1MAPTDGAT1 | |
| SCHEMBL31416815 | 0.72 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL15351865 | 0.72 | NPC1 (0.42) | NPC1MAPTDGAT1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |