Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22731959 | 0.79 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL3708356 | 0.79 | PDE2A (0.39) | PDE2A | |
| SCHEMBL23363400 | 0.76 | PDE2A (0.41) | PDE2A | |
| SCHEMBL29757459 | 0.76 | PDE2A (0.41) | PDE2A | |
| SCHEMBL21591667 | 0.76 | PDE2A (0.31) | PDE2A | |
| SCHEMBL1584418 | 0.72 | UGT2B7 (0.31) | PDE2AUGT2B7 | |
| SCHEMBL29844646 | 0.72 | UGT2B7 (0.31) | PDE2AUGT2B7 | |
| SCHEMBL24742242 | 0.67 | — | — | |
| SCHEMBL31586464 | 0.67 | — | — | |
| SCHEMBL5696452 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |