Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23363400 | 1.00 | PDE2A (0.41) | PDE2AKCNH2FFAR2 | |
| SCHEMBL18368368 | 0.83 | LMNA (0.33) | — | |
| SCHEMBL25053869 | 0.79 | PDE2A (0.42) | PDE2AKCNH2 | |
| SCHEMBL3708356 | 0.79 | PDE2A (0.39) | PDE2AKCNH2 | |
| SCHEMBL3617710 | 0.79 | PDE2A (0.35) | PDE2A | |
| SCHEMBL23363065 | 0.78 | PDE2A (0.34) | PDE2A | |
| SCHEMBL23363064 | 0.78 | PDE2A (0.34) | PDE2A | |
| SCHEMBL29757466 | 0.78 | PDE2A (0.34) | PDE2A | |
| SCHEMBL31416770 | 0.76 | PDE2A (0.37) | PDE2A | |
| SCHEMBL31416829 | 0.72 | PDE2A (0.41) | PDE2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867556-B | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4161641-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-4161936-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115867556-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |