Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417662 | 1.00 | CRBN (0.41) | CRBNDDB1HPGDSTRPV1IKZF3 | |
| SCHEMBL31417764 | 0.85 | TRPV1 (0.33) | CRBNDDB1TRPV1CSNK1A1IKZF2 | |
| SCHEMBL31417719 | 0.85 | TRPV1 (0.33) | CRBNDDB1TRPV1CSNK1A1IKZF2 | |
| SCHEMBL31417524 | 0.85 | HPGDS (0.40) | CRBNDDB1HPGDSTRPV1IKZF3 | |
| SCHEMBL31417766 | 0.82 | DHODH (0.37) | KDR | |
| SCHEMBL31417624 | 0.81 | MRGPRX4 (0.36) | TRPV1KDR | |
| SCHEMBL31417740 | 0.78 | TRPV1 (0.37) | CRBNDDB1TRPV1CSNK1A1IKZF2 | |
| SCHEMBL31417560 | 0.70 | TRPV1 (0.32) | CRBNDDB1TRPV1CSNK1A1IKZF2 | |
| SCHEMBL20812660 | 0.69 | CRBN (0.65) | CRBNDDB1HPGDSIKZF3GSPT1 | |
| SCHEMBL31438897 | 0.69 | CRBN (0.51) | CRBNDDB1CSNK1A1IKZF2GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016457-A1 | NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR | 杭州德睿智药科技有限公司 | 2025-01-23 | — | — | WO | disclosed |