Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 15/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712036 | 0.82 | CLK1 (0.45) | CLK1DYRK1AMTNR1AMTNR1BHTR2C | |
| SCHEMBL1712516 | 0.81 | MTNR1A (0.37) | MTNR1AMTNR1BHTR2CPTGS2NQO2 | |
| SCHEMBL1712254 | 0.81 | MTNR1A (0.37) | MTNR1AMTNR1BHTR2CPTGS2NQO2 | |
| SCHEMBL1712179 | 0.80 | MTNR1A (0.39) | MTNR1AMTNR1BHTR2CPTGS2 | |
| SCHEMBL28792431 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1BHTR2CPTGS2NQO2 | |
| SCHEMBL3149015 | 0.75 | MTNR1A (0.41) | MTNR1AMTNR1BHTR2CPTGS2 | |
| SCHEMBL3142042 | 0.72 | NQO2 (0.38) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL31575293 | 0.71 | CLK1 (0.39) | CLK1DYRK1A | |
| SCHEMBL23208944 | 0.70 | MTNR1A (0.35) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL29970846 | 0.70 | MTNR1A (0.35) | MTNR1AMTNR1BHTR2CNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954697-B1 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2010-02-24 | — | — | EP | disclosed |