Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 6/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 6/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661522 | 0.85 | PKM (0.41) | BCL6TRIM24IRAK4PKMIDO1 | |
| SCHEMBL26621509 | 0.85 | PKM (0.41) | BCL6TRIM24IRAK4PKMIDO1 | |
| SCHEMBL30661548 | 0.84 | PKM (0.43) | BCL6TRIM24IRAK4PKMINSR | |
| SCHEMBL26621447 | 0.84 | PKM (0.43) | BCL6TRIM24IRAK4PKMINSR | |
| SCHEMBL30661653 | 0.82 | TRIM24 (0.44) | BCL6TRIM24IRAK4PKMINSR | |
| SCHEMBL26621491 | 0.82 | TRIM24 (0.44) | BCL6TRIM24IRAK4PKMINSR | |
| SCHEMBL26621432 | 0.81 | PKM (0.42) | BCL6TRIM24IRAK4PKMIDO1 | |
| SCHEMBL31419454 | 0.81 | PKM (0.42) | BCL6TRIM24IRAK4PKMIDO1 | |
| SCHEMBL30904731 | 0.75 | BCL6 (0.69) | BCL6TRIM24 | |
| SCHEMBL20568882 | 0.75 | BCL6 (0.69) | BCL6TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604493-A | Heterocyclic compounds as BCL6 modulators useful as ligand-directed degradants | 细胞基因公司 | 2025-03-11 | — | — | CN | disclosed |