Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ME2 | P23368 | 1/20 | 0.58 |
| ▸ | ME1 | P48163 | 1/20 | 0.58 |
| ▸ | ME3 | Q16798 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131839 | 0.87 | NPC1 (0.86) | TSHRNPC1TDP1SIGMAR1FKBP1A | |
| SCHEMBL14100159 | 0.85 | TSHR (0.72) | TSHRKDM4ENPC1TDP1SIGMAR1 | |
| SCHEMBL9819732 | 0.84 | TSHR (0.71) | TSHRNPC1TDP1SIGMAR1FKBP1A | |
| SCHEMBL10975702 | 0.84 | TSHR (0.71) | TSHRKDM4ESIGMAR1L3MBTL1ME2 | |
| SCHEMBL2377541 | 0.84 | TSHR (0.70) | TSHRKDM4ENPC1TDP1SIGMAR1 | |
| SCHEMBL10162567 | 0.83 | HSD11B1 (0.72) | TSHRKDM4ENPC1TDP1SIGMAR1 | |
| SCHEMBL10163014 | 0.83 | NPC1 (0.73) | TSHRNPC1TDP1SIGMAR1FKBP1A | |
| SCHEMBL31512422 | 0.81 | TSHR (0.66) | TSHRNPC1TDP1SIGMAR1FKBP1A | |
| SCHEMBL3796874 | 0.81 | NPC1 (0.75) | TSHRNPC1TDP1SIGMAR1FKBP1A | |
| SCHEMBL25432319 | 0.80 | NPC1 (0.93) | TSHRNPC1TDP1FKBP1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025058989-A1 | NOVEL COMPOUNDS FOR TREATING CANCER | MARSAL THERAPEUTICS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |