SCHEMBL31420201

SCHEMBL31420201

c1ccc(-c2ccc(C(OCCN3CCNCC3)c3ccccc3)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.86
SLC6A4 P31645 3/20 0.58
SLC6A3 Q01959 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2D6 P10635 2/20 0.58
TSHR P16473 2/20 0.58
CYP2C19 P33261 2/20 0.58
HIF1A Q16665 2/20 0.58
SLC6A2 P23975 2/20 0.58
CYP3A4 P08684 2/20 0.58
SLC22A1 O15245 1/20 0.58
CHRM2 P08172 1/20 0.58
HTR1A P08908 1/20 0.58
ADRA2A P08913 1/20 0.58
CHRM1 P11229 1/20 0.58
DRD1 P21728 1/20 0.58
TBXA2R P21731 1/20 0.58
ADRA1A P35348 1/20 0.58
OPRM1 P35372 1/20 0.58
DRD3 P35462 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6255520 0.93 SIGMAR1 (1.00) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL9242632 0.88 SIGMAR1 (0.84) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL9050633 0.88 SIGMAR1 (0.84) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL9240199 0.87 SIGMAR1 (0.89) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL27518935 0.85 SIGMAR1 (0.80) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL6985333 0.84 SIGMAR1 (0.83) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL10357800 0.83 SIGMAR1 (0.81) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL6981300 0.83 SIGMAR1 (0.81) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL6978898 0.82 SIGMAR1 (0.78) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL6976586 0.82 SIGMAR1 (0.78) SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025058989-A1 NOVEL COMPOUNDS FOR TREATING CANCER MARSAL THERAPEUTICS, INC. (US) 2025-03-20 WO disclosed