SCHEMBL31420396

SCHEMBL31420396

CCCCCCCCC(CN(CCCN(CC)CC)CC(CCCCCCCC)OC(=O)CCCCCCC)OC(=O)CCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 2/20 0.53
MAPK1 P28482 2/20 0.53
PRKCA P17252 1/20 0.47
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCD Q05655 1/20 0.47
TLR2 O60603 1/20 0.46
LPAR3 Q9UBY5 6/20 0.45
LPAR1 Q92633 3/20 0.45
ENPP2 Q13822 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LPAR2 Q9HBW0 2/20 0.44
MEN1 O00255 1/20 0.44
GMNN O75496 1/20 0.44
HSP90AA1 P07900 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31420381 0.96 LMNA (0.55) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420408 0.92 LMNA (0.56) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420383 0.91 LMNA (0.59) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420427 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420425 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420416 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420397 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420388 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420439 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA
SCHEMBL31420373 0.90 LMNA (0.52) LMNAALDH1A1MAPTMAPK1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059107-A1 DEGRADABLE, BRANCHED LIPID COMPOUNDS, METHODS OF PREPARATION THEREOF, LIPID NANOPARTICLES (LNPS) COMPRISING THE SAME, AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-03-20 WO claimed
WO-2025059107-A1 DEGRADABLE, BRANCHED LIPID COMPOUNDS, METHODS OF PREPARATION THEREOF, LIPID NANOPARTICLES (LNPS) COMPRISING THE SAME, AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-03-20 WO disclosed