SCHEMBL31420838

SCHEMBL31420838

COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(=O)NCC2CCC2)cc1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.66
▸ CYP2D6 P10635 3/20 0.66
▸ SMN1; SMN2 Q16637 3/20 0.66
▸ KMT2A Q03164 2/20 0.66
▸ LMNA P02545 1/20 0.66
▸ MAPK1 P28482 1/20 0.66
▸ HIF1A Q16665 1/20 0.66
▸ MEN1 O00255 1/20 0.66
▸ CYP2C9 P11712 1/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ SLC2A1 P11166 1/20 0.66
▸ POLB P06746 1/20 0.39
▸ BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31420620 0.96 SMN1; SMN2 (0.69) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31421143 0.92 SMN1; SMN2 (0.64) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31421384 0.92 SMN1; SMN2 (0.69) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31421362 0.91 ALDH1A1 (0.60) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31421223 0.91 ALDH1A1 (0.60) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31420549 0.89 SMN1; SMN2 (0.62) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31420826 0.89 SMN1; SMN2 (0.62) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31421136 0.89 SMN1; SMN2 (0.65) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31420590 0.88 SMN1; SMN2 (0.64) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA
SCHEMBL31421138 0.87 SMN1; SMN2 (0.62) ALDH1A1CYP2D6SMN1; SMN2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ALDH1A1 2630/4885CYP2D6 2401/4885SMN1; SMN2 1576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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