SCHEMBL31421086

SCHEMBL31421086

NC[C@H]1CCN(c2nccs2)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.42
BPTF Q12830 1/20 0.41
ALDH1A1 P00352 1/20 0.41
DRD2 P14416 1/20 0.41
MEN1 O00255 2/20 0.40
PRKCQ Q04759 1/20 0.40
HTT P42858 1/20 0.40
CHI3L1 P36222 1/20 0.38
CHIT1 Q13231 1/20 0.38
CHI3L2 Q15782 1/20 0.38
CHIA Q9BZP6 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
PBK Q96KB5 1/20 0.38
GRM5 P41594 1/20 0.37
GRM1 Q13255 1/20 0.37
KMT2A Q03164 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4423455 0.81 DRD2 (0.49) HPGDHSD17B10ALDH1A1DRD2MEN1
SCHEMBL1025896 0.80 HSD17B10 (0.50) HPGDHSD17B10ALDH1A1HTTHRH3
SCHEMBL2861212 0.79 HPGD (0.46) HPGDHSD17B10ALDH1A1DRD2MEN1
SCHEMBL1700773 0.78 HPGD (0.51) HPGDHSD17B10ALDH1A1DRD2MEN1
SCHEMBL6029924 0.78 MEN1 (0.49) HPGDHSD17B10ALDH1A1DRD2MEN1
Hydrochloric Acid SCHEMBL974366 0.78 HPGD (0.45) HPGDHSD17B10ALDH1A1DRD2MEN1
SCHEMBL6405599 0.76 HPGD (0.46) HPGDHSD17B10ALDH1A1DRD2MEN1
SCHEMBL4525966 0.76 HPGD (0.49) HPGDHSD17B10ALDH1A1MEN1HTT
SCHEMBL13035394 0.76 HPGD (0.46) HPGDHSD17B10ALDH1A1MEN1HTT
SCHEMBL4525971 0.76 HPGD (0.49) HPGDHSD17B10ALDH1A1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS HPGD 2011/4885HSD17B10 3549/4885BPTF 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.