SCHEMBL31421160

SCHEMBL31421160

CC(C)(C)OC(=O)NCCN1CCC2(CCC2)C1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 11/20 0.52
CACNA1H O95180 1/20 0.48
TDP1 Q9NUW8 1/20 0.41
EPHX1 P07099 1/20 0.41
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
SIGMAR1 Q99720 2/20 0.38
CD274 Q9NZQ7 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30202898 0.92 DRD2 (0.57) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL16231598 0.85 DRD2 (0.60) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL31420883 0.85 CACNA1H (0.51) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL24951903 0.84 DRD2 (0.55) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL15686281 0.82 DRD2 (0.53) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL16232049 0.81 DRD2 (0.55) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL4024516 0.81 DRD2 (0.56) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL31301250 0.81 DRD2 (0.56) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL24172673 0.81 DRD2 (0.56) DRD2CACNA1HTDP1EPHX1MEN1
SCHEMBL31301242 0.80 DRD2 (0.63) DRD2CACNA1HTDP1EPHX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS DRD2 2243/4885CACNA1H 4160/4885TDP1 3388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.