SCHEMBL31421174

SCHEMBL31421174

CC(C)(C)OC(=O)N1CCCC[C@H](CC#N)C1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.60
ALDH1A1 P00352 1/20 0.60
MAPT P10636 1/20 0.60
KMT2A Q03164 1/20 0.60
HPGD P15428 1/20 0.48
BACE1 P56817 2/20 0.44
CTSD P07339 1/20 0.44
CTSK P43235 3/20 0.43
GLS O94925 2/20 0.43
EPHX1 P07099 1/20 0.43
NR1H2 P55055 1/20 0.43
ACKR3 P25106 1/20 0.42
PREP P48147 2/20 0.41
KDM1A O60341 1/20 0.40
FEN1 P39748 1/20 0.40
SCN9A Q15858 1/20 0.40
CTSS P25774 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31420572 1.00 MEN1 (0.60) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL11995200 0.96 MEN1 (0.64) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL12940814 0.96 MEN1 (0.64) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL13542527 0.96 MEN1 (0.64) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL15626875 0.90 MEN1 (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL1773253 0.90 MEN1 (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL15626878 0.90 MEN1 (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL1772940 0.85 MEN1 (0.57) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL9696880 0.84 NR1H2 (0.54) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL30759088 0.84 MEN1 (0.52) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS MEN1 798/4885ALDH1A1 2630/4885MAPT 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.