Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422941 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31422769 | 0.96 | LMNA (0.40) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31422934 | 0.87 | MEN1 (0.41) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31423325 | 0.85 | HSD17B2 (0.42) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31422776 | 0.85 | LMNA (0.42) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31423295 | 0.85 | LMNA (0.42) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31422891 | 0.84 | LMNA (0.47) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31422766 | 0.83 | KMT2A (0.39) | MEN1KMT2ALMNACNR2JAK2 | |
| SCHEMBL31423169 | 0.82 | CNR2 (0.45) | MEN1KMT2ALMNACNR2HSD17B2 | |
| SCHEMBL31273362 | 0.79 | LMNA (0.44) | MEN1KMT2ALMNAJAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |