Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423016 | 0.81 | PGR (0.36) | KDM4EGAA | |
| SCHEMBL31422947 | 0.76 | PLA2G10 (0.38) | PLA2G10MAPK1 | |
| SCHEMBL31423112 | 0.73 | PARP1 (0.38) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL30174316 | 0.72 | NR4A1 (0.36) | ALDH1A1TSHRKDM4EREN | |
| SCHEMBL9849401 | 0.72 | DAO (0.50) | PLA2G10ALDH1A1TSHRMAPK1IRAK4 | |
| SCHEMBL28195486 | 0.71 | MAPT (0.39) | ALDH1A1TSHRKDM4EDDB1CRBN | |
| SCHEMBL29932906 | 0.71 | DAO (0.60) | ALDH1A1MAPK1IRAK4IKBKBKDM4E | |
| SCHEMBL11983168 | 0.71 | DAO (0.60) | ALDH1A1MAPK1IRAK4IKBKBKDM4E | |
| SCHEMBL28196196 | 0.71 | NOTUM (0.40) | PLA2G10ALDH1A1TSHRRENNOTUM | |
| Formic Acid SCHEMBL25274480 | 0.70 | PARP1 (0.41) | PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |