Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1174115 | 1.00 | AR (0.63) | ARCYP1A2CYP2C19TNKS2KDM4E | |
| SCHEMBL15828556 | 0.81 | CYP1A2 (0.61) | ARCYP1A2CYP2C19TNKS2KDM4E | |
| SCHEMBL1771872 | 0.80 | AR (0.61) | ARTNKS2 | |
| SCHEMBL14969318 | 0.80 | AR (0.49) | AR | |
| SCHEMBL1771008 | 0.79 | AR (0.69) | AR | |
| SCHEMBL1771152 | 0.79 | AR (0.69) | AR | |
| SCHEMBL13429043 | 0.78 | KIF11 (0.45) | ARCYP1A2CYP2C19TNKS2KDM4E | |
| SCHEMBL30946245 | 0.78 | KIF11 (0.51) | ARKDM4EALDH1A1HPGDHTT | |
| SCHEMBL3787127 | 0.78 | KIF11 (0.51) | ARKDM4EALDH1A1HPGDHTT | |
| SCHEMBL31331602 | 0.77 | AR (1.00) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |