SCHEMBL31423609

SCHEMBL31423609

CC(C)c1ccccc1-c1ncc(C(F)(F)F)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.62
▸ WDR48 Q8TAF3 16/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30135346 0.91 USP1 (0.68) USP1WDR48
SCHEMBL18865831 0.91 USP1 (0.68) USP1WDR48
SCHEMBL29691163 0.91 USP1 (0.68) USP1WDR48
SCHEMBL31423524 0.91 USP1 (0.64) USP1WDR48
SCHEMBL27086733 0.91 USP1 (0.68) USP1WDR48
SCHEMBL30135370 0.89 USP1 (0.60) USP1WDR48
SCHEMBL27086985 0.89 USP1 (0.60) USP1WDR48
SCHEMBL31423670 0.89 USP1 (0.63) USP1WDR48
SCHEMBL27087040 0.89 USP1 (0.60) USP1WDR48
SCHEMBL31423496 0.88 USP1 (0.59) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741386-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-13 — — EP disclosed
EP-4516779-A1 PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2025-03-05 — — EP disclosed
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