SCHEMBL31423729

SCHEMBL31423729

CC(C)(C)[S@@+]([O-])N[C@@H](Cc1coc2ccccc12)B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 14/20 0.38
PSMB8 P28062 4/20 0.38
CA2 P00918 1/20 0.35
ANPEP P15144 1/20 0.34
LAP3 P28838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26692139 1.00 PSMB5 (0.38) PSMB5PSMB8CA2ANPEPLAP3
SCHEMBL26692146 1.00 PSMB5 (0.38) PSMB5PSMB8CA2ANPEPLAP3
SCHEMBL26692141 1.00 PSMB5 (0.38) PSMB5PSMB8CA2ANPEPLAP3
SCHEMBL20764142 0.79 ANPEP (0.50) PSMB5ANPEPLAP3
Hydrochloric Acid SCHEMBL26692120 0.74 ANPEP (0.56) PSMB5PSMB8CA2ANPEPLAP3
Hydrochloric Acid SCHEMBL31423718 0.74 ANPEP (0.56) PSMB5PSMB8CA2ANPEPLAP3
Hydrochloric Acid SCHEMBL26692117 0.74 ANPEP (0.56) PSMB5PSMB8CA2ANPEPLAP3
SCHEMBL31423666 0.73 ANPEP (0.37) PSMB5ANPEPLAP3
SCHEMBL20401414 0.72 ANPEP (0.42) ANPEPLAP3
SCHEMBL20401416 0.72 ANPEP (0.42) ANPEPLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346613-A1 BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF ARTIVILA BIOPHARMA (CN) 2025-11-13 US disclosed
EP-4516796-A1 BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF Artivila Biopharma (CN) 2025-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346613-A1 BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF PSMA1, PSMB11, PSMB1 PSMB5 12/4885PSMB8 20/4885CA2 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.