SCHEMBL31423765

SCHEMBL31423765

NC(=O)c1cnc(N)c([N+](=O)[O-])c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.46
CYP3A4 P08684 1/20 0.46
LMNA P02545 7/20 0.44
MET P08581 1/20 0.43
ALDH1A1 P00352 3/20 0.42
GAA P10253 3/20 0.42
PKM P14618 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 2/20 0.42
NNMT P40261 1/20 0.42
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CASP6 P55212 1/20 0.40
ATM Q13315 1/20 0.39
CTPS1 P17812 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4170811 1.00 PARP1 (0.50) PARP1SMN1; SMN2CYP3A4LMNAMET
SCHEMBL31423772 0.86 LMNA (0.56) LMNAMETALDH1A1TSHRKDM4E
SCHEMBL712818 0.86 LMNA (0.56) LMNAMETALDH1A1TSHRKDM4E
SCHEMBL31423773 0.86 LMNA (0.56) LMNAMETALDH1A1TSHRKDM4E
SCHEMBL2303103 0.85 LMNA (0.42) PARP1CYP3A4LMNAALDH1A1TSHR
SCHEMBL7180111 0.83 PARP1 (0.50) PARP1SMN1; SMN2CYP3A4LMNAMET
SCHEMBL805262 0.81 PARP1 (0.49) PARP1SMN1; SMN2CYP3A4LMNAMET
SCHEMBL16095613 0.81 PARP1 (0.49) PARP1SMN1; SMN2CYP3A4LMNAMET
SCHEMBL5248286 0.81 MAPK1 (0.56) ALDH1A1L3MBTL1MAPTKDM4EMEN1
SCHEMBL27488036 0.79 LMNA (0.41) PARP1SMN1; SMN2LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530294-B Aryl diamine immobilized linker, precursor thereof, preparation method and application 浙江大学 2025-02-14 CN disclosed