Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423973 | 0.87 | CD274 (0.35) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31423944 | 0.85 | CD274 (0.36) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31423890 | 0.85 | JAK2 (0.36) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL25227147 | 0.81 | CD274 (0.39) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL23209298 | 0.78 | JAK2 (0.42) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL23209288 | 0.78 | JAK2 (0.40) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31423989 | 0.78 | JAK2 (0.40) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31318302 | 0.76 | CD274 (0.38) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31318303 | 0.76 | CD274 (0.38) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31458579 | 0.74 | JAK2 (0.36) | CD274JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054386-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |