Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423919 | 0.85 | CD274 (0.40) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31423896 | 0.81 | PIM1 (0.40) | JAK1PIM1MKNK1CCNE1CDK2 | |
| SCHEMBL31423880 | 0.80 | JAK2 (0.39) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31424012 | 0.80 | JAK2 (0.36) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31458674 | 0.78 | JAK2 (0.34) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31423973 | 0.75 | CD274 (0.35) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL25227147 | 0.73 | CD274 (0.39) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31423890 | 0.72 | JAK2 (0.36) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31318302 | 0.72 | CD274 (0.38) | CD274JAK2JAK1TYK2JAK3 | |
| SCHEMBL31318303 | 0.72 | CD274 (0.38) | CD274JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054386-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |