Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.48 |
| ▸ | JAK1 | P23458 | 5/20 | 0.46 |
| ▸ | TYK2 | P29597 | 3/20 | 0.46 |
| ▸ | JAK3 | P52333 | 3/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29885909 | 0.85 | JAK2 (0.44) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL23209401 | 0.85 | JAK2 (0.44) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL30043068 | 0.85 | JAK2 (0.48) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL23209359 | 0.85 | JAK2 (0.48) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31423892 | 0.84 | JAK2 (0.43) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31423990 | 0.84 | JAK2 (0.42) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL24849568 | 0.83 | JAK2 (0.45) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31318300 | 0.82 | JAK2 (0.44) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31318305 | 0.82 | JAK2 (0.44) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31318301 | 0.81 | JAK2 (0.44) | JAK2JAK1TYK2JAK3MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096061-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025054386-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |