Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 3/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423933 | 0.89 | NTRK1 (0.34) | NTRK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31423902 | 0.89 | NTRK1 (0.34) | NTRK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31423937 | 0.89 | NTRK1 (0.34) | NTRK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31423948 | 0.89 | NTRK1 (0.34) | NTRK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31423966 | 0.89 | NTRK1 (0.34) | NTRK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31458611 | 0.84 | PIK3CA (0.34) | NTRK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31423905 | 0.83 | MAPK8 (0.40) | NTRK1JAK2JAK3MARK3 | |
| SCHEMBL23209263 | 0.81 | JAK1 (0.31) | JAK2JAK1 | |
| SCHEMBL23209264 | 0.81 | CCNE1 (0.42) | CCNT1CCNE1CDK2CDK9JAK2 | |
| SCHEMBL30062031 | 0.80 | CDK6 (0.36) | CCNE1CDK2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054386-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |