Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23209353 | 0.87 | ROCK2 (0.33) | JAK1JAK2 | |
| SCHEMBL23209264 | 0.86 | CCNE1 (0.42) | JAK1JAK2 | |
| SCHEMBL23209335 | 0.86 | WNT1 (0.35) | JAK1JAK2 | |
| SCHEMBL23209306 | 0.85 | JAK1 (0.34) | JAK1JAK2 | |
| SCHEMBL23209563 | 0.83 | JAK1 (0.36) | JAK1JAK2 | |
| SCHEMBL23209302 | 0.82 | JAK1 (0.34) | JAK1JAK2 | |
| SCHEMBL23209441 | 0.81 | ROCK2 (0.34) | JAK1JAK2 | |
| SCHEMBL31423943 | 0.81 | NTRK1 (0.35) | JAK1JAK2 | |
| SCHEMBL23209445 | 0.79 | CDK4 (0.40) | JAK1JAK2 | |
| SCHEMBL23209223 | 0.76 | JAK1 (0.44) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107901-A1 | BICYCLIC AMINES AS CDK2 INHIBITORS | INCYTE CORPORATION | 2021-04-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107901-A1 | BICYCLIC AMINES AS CDK2 INHIBITORS | CDK2, CDK1, CCNI | JAK1 932/4885JAK2 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.