Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589714 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1KDM4ETP53 | |
| SCHEMBL27356467 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL27447092 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK1KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL3142402 | 0.76 | MAPT (0.50) | ALDH1A1MAPTRAB9AKDM4ELMNA | |
| SCHEMBL27779069 | 0.75 | ALDH1A1 (0.32) | ALDH1A1SRD5A1SRD5A2CYP2D6CYP2C19 | |
| SCHEMBL8766396 | 0.73 | CA1 (0.47) | ALDH1A1MAPTSMN1; SMN2TRPA1KDM4E | |
| SCHEMBL14692395 | 0.73 | GSK3B (0.50) | GSK3BALDH1A1MAPTSMN1; SMN2HIF1A | |
| Trifluoroacetic Acid SCHEMBL27357823 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2MAPK1KDM4E | |
| SCHEMBL11679626 | 0.72 | MAPT (0.58) | GSK3BALDH1A1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL14692502 | 0.72 | SRD5A2 (0.54) | GSK3BALDH1A1MAPTSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151846-B1 | High temperature thermal cutoff device | THERM O DISC INC (US) | 2013-10-09 | — | — | EP | disclosed |
| EP-2151846-A2 | High temperature thermal cutoff device | Therm-O-Disc Incorporated (US) | 2010-02-10 | — | — | EP | disclosed |