Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425650 | 0.78 | PDE3B (0.49) | PGRCYP3A4MAPTALDH1A1THRB | |
| SCHEMBL29703162 | 0.73 | PGR (0.52) | PGRPOLBMAOB | |
| SCHEMBL15749197 | 0.73 | PGR (0.52) | PGRPOLBMAOB | |
| SCHEMBL18238156 | 0.72 | POLB (0.47) | PGRPOLBCYP3A4CYP2B6MAOB | |
| SCHEMBL19174042 | 0.72 | — | — | |
| SCHEMBL17807828 | 0.70 | MAOB (0.44) | PGRPOLBCYP3A4CYP2B6MAOB | |
| SCHEMBL19836475 | 0.70 | AURKA (0.42) | PGRPOLBMAOBMTORMAPT | |
| SCHEMBL828859 | 0.70 | POLB (0.41) | PGRPOLBCYP3A4CYP2B6MAOB | |
| SCHEMBL15740630 | 0.70 | PGR (0.49) | PGRPOLBMAOBCCR4MAPT | |
| SCHEMBL31425662 | 0.69 | HSD17B10 (0.40) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604505-A | Heterocyclic compounds for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2025-03-11 | — | — | CN | disclosed |