Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 7/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618046 | 1.00 | PDE2A (0.39) | PDE2ACDK4GRM5PDGFRBPDGFRA | |
| SCHEMBL26618169 | 0.77 | CDK4 (0.36) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL30643012 | 0.77 | CDK4 (0.36) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL3410707 | 0.76 | CDK4 (0.40) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL19899744 | 0.75 | FFAR4 (0.41) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL11788449 | 0.74 | GRM5 (0.42) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL19862428 | 0.73 | CDK4 (0.41) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL19510918 | 0.72 | FFAR4 (0.39) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL23790497 | 0.71 | LRRK2 (0.44) | CDK4GRM5PDGFRBPDGFRAFFAR4 | |
| SCHEMBL30775428 | 0.68 | HRH1 (0.43) | LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451951-A | Compounds for inhibition of KIF18A | 沃拉斯查疗法公司 | 2025-02-14 | — | — | CN | disclosed |