Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30713310 | 0.93 | CSNK1E (0.75) | CSNK1E | |
| SCHEMBL15891060 | 0.93 | CSNK1E (0.75) | CSNK1E | |
| SCHEMBL14841543 | 0.90 | CSNK1E (0.71) | CSNK1E | |
| SCHEMBL30713372 | 0.90 | CSNK1E (0.71) | CSNK1E | |
| SCHEMBL14841656 | 0.84 | CSNK1E (0.87) | CSNK1E | |
| SCHEMBL30713359 | 0.83 | CSNK1E (1.00) | CSNK1E | |
| SCHEMBL15890845 | 0.83 | CSNK1E (1.00) | CSNK1E | |
| SCHEMBL31219 | 0.83 | CSNK1E (1.00) | CSNK1E | |
| SCHEMBL14841557 | 0.83 | CSNK1E (1.00) | CSNK1E | |
| SCHEMBL30713315 | 0.83 | CSNK1E (1.00) | CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161537-A2 | 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-29 | — | — | WO | disclosed |