SCHEMBL31427151

SCHEMBL31427151

[2H]C(O)[C@H]1O[C@@](CCC(=C)C)(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GMPS P49915 1/20 0.50
ADORA3 P0DMS8 4/20 0.45
ADORA2A P29274 3/20 0.45
PI4KA P42356 3/20 0.41
PI4K2B Q8TCG2 3/20 0.41
PI4K2A Q9BTU6 3/20 0.41
PI4KB Q9UBF8 3/20 0.41
SLC28A1 O00337 2/20 0.41
DPP4 P27487 1/20 0.41
MEN1 O00255 1/20 0.41
MAP3K7 O43318 1/20 0.41
SLC28A2 O43868 1/20 0.41
GAPDH P04406 1/20 0.41
MAPK1 P28482 1/20 0.41
ADORA2B P29275 1/20 0.41
ADORA1 P30542 1/20 0.41
STAT6 P42226 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
DOT1L Q8TEK3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184433 0.92 GMPS (0.52) GMPSADORA3ADORA2API4KAPI4K2B
SCHEMBL552798 0.92 GMPS (0.52) GMPSADORA3ADORA2API4KAPI4K2B
Triphosphate SCHEMBL28183622 0.84 P2RY2 (0.47) GMPSADORA3ADORA2AADORA1SMN1; SMN2
SCHEMBL29663587 0.83 P2RY1 (0.53) ADORA1SMN1; SMN2
SCHEMBL1262939 0.83 P2RY1 (0.53) ADORA1SMN1; SMN2
Adenine SCHEMBL28771594 0.82 GMPS (0.43) GMPSADORA3ADORA2API4KAPI4K2B
SCHEMBL1263520 0.81 P2RX1 (0.54) SMN1; SMN2
SCHEMBL2534138 0.81 ADORA3 (0.52) GMPSADORA3ADORA2API4KAPI4K2B
SCHEMBL29639535 0.80 ADORA3 (0.54) GMPSADORA3ADORA2API4KAPI4K2B
SCHEMBL2270714 0.80 ADORA3 (0.54) GMPSADORA3ADORA2API4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197898-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE PRODUCTS AND METHOD OF PREPARATION THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-06-19 US disclosed
US-12227780-B2 Isothiocyanate containing Brassicaceae products and method of preparation thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-02-18 US disclosed