Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428515 | 0.86 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL31428571 | 0.79 | HPGD (0.45) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL31428951 | 0.76 | HPGD (0.53) | RAB9ANPC1ALDH1A1 | |
| SCHEMBL24976088 | 0.76 | NPC1 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C9KDM2B | |
| SCHEMBL31428645 | 0.75 | HPGD (0.57) | TSHRGLAALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL30163530 | 0.75 | SCN9A (0.54) | TSHRKDM2B | |
| SCHEMBL8867058 | 0.75 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL31428578 | 0.75 | L3MBTL3 (0.59) | ALDH1A1KMT2AL3MBTL3L3MBTL1MEN1 | |
| SCHEMBL31429017 | 0.74 | MEN1 (0.51) | CYP1A2KDM2BRAB9ANPC1ALDH1A1 | |
| SCHEMBL31428637 | 0.74 | HPGD (0.47) | CYP1A2TSHRKDM2BRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | CYP1A2 3982/4885CYP3A4 4009/4885CYP2D6 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.