Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9907331 | 0.82 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL538292 | 0.81 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL31428806 | 0.80 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL31428582 | 0.80 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL31428597 | 0.80 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL24975631 | 0.80 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL16621161 | 0.80 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL3879992 | 0.77 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL31429002 | 0.76 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TP53MAPTKDM4E | |
| SCHEMBL24975629 | 0.76 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885L3MBTL1 1560/4885TP53 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.