Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428704 | 0.88 | ALDH1A1 (0.52) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31428701 | 0.86 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL31429054 | 0.85 | LRRK2 (0.34) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL31428613 | 0.85 | PDCD1 (0.38) | ALDH1A1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL31428635 | 0.85 | PDCD1 (0.38) | ALDH1A1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL31428556 | 0.84 | PDCD1 (0.37) | ALDH1A1SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL31428674 | 0.84 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TSHRHTTMAPT | |
| SCHEMBL31428450 | 0.84 | ACACB (0.34) | ALDH1A1SMN1; SMN2TSHRHTTLMNA | |
| SCHEMBL31428769 | 0.82 | LRRK2 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31428694 | 0.79 | ALDH1A1 (0.49) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | POLB 3285/4885MEN1 1712/4885KMT2A 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.