Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428880 | 0.91 | ALDH1A1 (0.43) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL24977060 | 0.90 | HTT (0.37) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428665 | 0.90 | HTT (0.37) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428878 | 0.88 | MAPT (0.44) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428889 | 0.88 | PDCD1 (0.41) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428638 | 0.86 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428974 | 0.85 | MAPT (0.41) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428957 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428569 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31428736 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HTTMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885HTT 4442/4885MAPT 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.