Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163485 | 0.90 | MAPT (0.53) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL30163547 | 0.83 | ALDH1A1 (0.53) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL31428729 | 0.81 | ALDH1A1 (0.54) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL31428779 | 0.80 | ALDH1A1 (0.50) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL31428668 | 0.79 | ALDH1A1 (0.53) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL31428936 | 0.78 | ALDH1A1 (0.59) | KMT2AMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL31428792 | 0.78 | ALDH1A1 (0.53) | KMT2AMAPTALDH1A1MEN1AKR1B1 | |
| SCHEMBL31428526 | 0.78 | ALDH1A1 (0.53) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL31428917 | 0.77 | MAPT (0.52) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL31429081 | 0.77 | MAPT (0.53) | KMT2AMAPTLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | KMT2A 2837/4885MAPT 4513/4885LMNA 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.