Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163520 | 0.84 | MAPT (0.54) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31428670 | 0.84 | MAPT (0.54) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31428528 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31428451 | 0.83 | MAPT (0.49) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31428667 | 0.80 | MAPT (0.46) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL30163486 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL30163521 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31428617 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31428929 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL31428503 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885MAPT 4513/4885HTT 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.