Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutarate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL3687196 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL1740443 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL5134529 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL3686349 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL162951 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL104914 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL3688894 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL4520000 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL1035895 | 0.92 | — | — | |
| Glutarate SCHEMBL1533372 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686133-B2 | CONTAINING LIGHT-INSENSITIVE SILVER SALTS OF ORGANIC CARBOXYLIC ACIDS WITH ONE OR MORE CARBOXYLIC ACID AND A BINDER, EXCLUSIVE OF SILVER SUCCINATE SIMILAR COMPOUNDS | AGFA-GEVAERT (BE) | 2004-02-03 | — | — | US | claimed |
| US-20030064328-A1 | Photothermographic materials processable at lower temperatures and recording processes therefor | AGFA-GEVAERT (BE) | 2003-04-03 | — | — | US | claimed |
| EP-1258775-A2 | Photothermographic materials and recording processes therefor | AGFA-GEVAERT N.V. (BE) | 2002-11-20 | — | — | EP | claimed |
| EP-1246001-A1 | Thermographic materials and recording processes therefor | Agfa-Gevaert (BE) | 2002-10-02 | — | — | EP | claimed |
| US-4342667-A | Process for preparing a silver catalyst | THE HALCON SD GROUP, INC. (US) | 1982-08-03 | — | — | US | claimed |
| WO-2025033020-A1 | THERMALLY CONDUCTIVE COMPOSITION, METHOD FOR PRODUCING LAMINATE, AND LAMINATE | デクセリアルズ株式会社 | 2025-02-13 | — | — | WO | disclosed |
| WO-2025033013-A1 | LAMINATE AND METHOD FOR PRODUCING SAME | デクセリアルズ株式会社 | 2025-02-13 | — | — | WO | disclosed |
| CN-119212867-A | Laminate and method for producing same | 迪睿合株式会社 | 2024-12-27 | — | — | CN | disclosed |
| CN-119212868-A | Laminate and method for producing same | 迪睿合株式会社 | 2024-12-27 | — | — | CN | disclosed |
| CN-119156282-A | Laminate and method for producing same | 迪睿合株式会社 | 2024-12-17 | — | — | CN | disclosed |
| US-20240384147-A1 | THERMALLY CONDUCTIVE COMPOSITION AND THERMALLY CONDUCTIVE SHEET | DEXERIALS CORPORATION (JP) | 2024-11-21 | — | — | US | disclosed |
| CN-117916877-A | Thermally conductive composition and thermally conductive sheet | 迪睿合株式会社 | 2024-04-19 | — | — | CN | disclosed |
| EP-1246001-A1 | Thermographic materials and recording processes therefor | Agfa-Gevaert (BE) | 2002-10-02 | — | — | EP | disclosed |
| US-4866092-A | TREATING TUMORS IN MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1989-09-12 | — | — | US | disclosed |
| US-4675336-A | ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| US-4258129-A | IMPROVE GREEN SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-24 | — | — | US | disclosed |
| US-4211839-A | SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-08 | — | — | US | disclosed |
| US-4188212-A | BEZNOTRIAZOLE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |
| US-4180660-A | CONTAINING FORMYL SUBSTITUTED PYRROLE GROUP | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1979-12-25 | — | — | US | disclosed |
| US-4122260-A | CONTAINING FORMYL SUBSTITUTED PYRROLE, ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-10-24 | — | — | US | disclosed |