Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Glutarate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL106584 | 0.96 | CA1 (0.55) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL8745235 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL106537 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL5650126 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL8618874 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL5142628 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL2067310 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL5650130 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL5142631 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL3142994 | 0.92 | CA1 (0.58) | CA1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669434-A | Tin oxide electron transport layer modified in situ by aliphatic carboxylic acid potassium salt, high-performance photovoltaic cell and preparation method thereof | 武汉理工大学 | 2023-08-29 | — | — | CN | claimed |
| CN-111185071-B | Carbon dioxide absorbent and preparation method and application thereof | 国家能源投资集团有限责任公司 | 2022-03-11 | — | — | CN | claimed |
| CN-108059376-B | Preparation method of dental model gypsum | 青岛大学附属医院 | 2020-12-08 | — | — | CN | claimed |
| CN-111185071-A | Carbon dioxide absorbent and preparation method and application thereof | 国家能源投资集团有限责任公司 | 2020-05-22 | — | — | CN | claimed |
| US-20200071262-A1 | METHOD FOR PRODUCING ADIPAMIDE AS INTERMEDIATE FOR PRODUCTION OF RAW MATERIAL FOR BIO-BASED NYLON | HYUNDAI MOTOR COMPANY (KR) | 2020-03-05 | — | — | US | claimed |
| US-10508060-B1 | Fertilizer with organic potassium salts | Nachurs Alpine Solutions, Corp. (US) | 2019-12-17 | — | — | US | claimed |
| US-20180258001-A1 | Fertilizer for Salt-Sensitive Crops | Nachurs Alpine Solutions, Corp. (US) | 2018-09-13 | — | — | US | claimed |
| US-20180244589-A1 | Fertilizer with Organic Potassium Salts | Nachurs Alpine Solutions, Corp. (US) | 2018-08-30 | — | — | US | claimed |
| CN-108147447-A | A kind of liquid phase method prepares the processing technology of alpha semi-hydrated gypsum | 应城市嘉鸿技术服务科技有限公司 | 2018-06-12 | — | — | CN | claimed |
| CN-108059376-A | A kind of preparation method of dental models gypsum | 应城市嘉鸿技术服务科技有限公司 | 2018-05-22 | — | — | CN | claimed |
| US-9034810-B2 | Processing agent composition for semiconductor surface and method for processing semiconductor surface using same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2015-05-19 | — | — | US | claimed |
| WO-2012143794-A1 | POLYMER STABILIZER SYSTEM FOR POLYMERS CONTAINING HALOGEN | GALATA CHEMICALS GMBH (DE) | 2012-10-26 | — | — | WO | claimed |
| EP-2475000-A1 | PROCESSING AGENT COMPOSITION FOR SEMICONDUCTOR SURFACE AND METHOD FOR PROCESSING SEMICONDUCTOR SURFACE USING SAME | Wako Pure Chemical Industries, Ltd. (JP) | 2012-07-11 | — | — | EP | claimed |
| US-20120157368-A1 | PROCESSING AGENT COMPOSITION FOR SEMICONDUCTOR SURFACE AND METHOD FOR PROCESSING SEMICONDUCTOR SURFACE USING SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-21 | — | — | US | claimed |
| WO-2009010464-A1 | BEVERAGE WITH HIGH AMOUNT OF POTASSIUM | UNILEVER N.V. (NL) | 2009-01-22 | — | — | WO | claimed |
| US-20080260948-A1 | INK AND INK JET RECORDING METHOD | CANON KABUSHIKI KAISHA (JP) | 2008-10-23 | — | — | US | claimed |
| EP-0164908-B1 | PROCESS FOR PREPARATION OF COMPOSITIONS FOR MODIFYING PLANT GROWTH; COMPOSITION FOR PLANT GROWTH MODIFICATION: AND METHOD FOR THE USE THEREOF | ACTAGRO, INC. (US) | 1989-09-13 | — | — | EP | claimed |
| EP-0164908-A1 | Process for preparation of compositions for modifying plant growth; composition for plant growth modification: and method for the use thereof | ACTAGRO, INC. (US) | 1985-12-18 | — | — | EP | claimed |
| US-4448702-A | Freezing-point-lowering composition and method | LANG & CO., CHEMISCH-TECHNISCHE PRODUKTE KOMMANDITGESELLSCHAFT (AT) | 1984-05-15 | — | — | US | claimed |
| US-4200586-A | Inhibiting the carbon-carbon double bond isomerization of substituted or unsubstituted hydrocarbon compounds | PHILLIPS PETROLEUM COMPANY (US) | 1980-04-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071262-A1 | METHOD FOR PRODUCING ADIPAMIDE AS INTERMEDIATE FOR PRODUCTION OF RAW MATERIAL FOR BIO-BASED NYLON | IDH2, HK2, SLC2A2 | CA1 1451/4885HDAC3 725/4885HDAC1 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.