Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150933 | 0.90 | GCK (0.39) | GCKCYP11B1CYP11B2 | |
| SCHEMBL3155310 | 0.87 | ABL1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL3151010 | 0.87 | PDE3B (0.34) | GCK | |
| Hydrochloric Acid SCHEMBL3779595 | 0.86 | PDE3B (0.33) | GCK | |
| Hydrochloric Acid SCHEMBL3781610 | 0.82 | DHFR (0.34) | — | |
| Hydrochloric Acid SCHEMBL3776994 | 0.82 | MAP4K4 (0.38) | — | |
| Hydrochloric Acid SCHEMBL3782911 | 0.81 | DDT (0.39) | — | |
| SCHEMBL3137179 | 0.80 | CYP1A2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL3778995 | 0.80 | CHRNB4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL3776431 | 0.79 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |
| EP-1979321-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085750-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2007-08-02 | — | — | WO | disclosed |