SCHEMBL31432604

SCHEMBL31432604

COc1cc(CC(=O)OCC(C)C)ccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
ALDH1A1 P00352 1/20 0.61
GAA P10253 1/20 0.61
NFKB1 P19838 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
FOS P01100 1/20 0.55
TTR P02766 1/20 0.55
JUN P05412 1/20 0.55
NR3C1 P04150 1/20 0.55
HSD17B1 P14061 1/20 0.55
HSD17B2 P37059 1/20 0.55
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
ALOX5 P09917 1/20 0.50
OR51E2 Q9H255 1/20 0.50
CYP3A4 P08684 2/20 0.49
TAAR1 Q96RJ0 2/20 0.49
MMP1 P03956 1/20 0.49
MAPK1 P28482 1/20 0.49
IARS1 P41252 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17179836 1.00 TSHR (0.61) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL30168217 0.88 TSHR (0.57) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL17179838 0.88 TSHR (0.57) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL30242334 0.86 TSHR (0.58) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL19384144 0.86 ALDH1A1 (0.58) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL17179832 0.86 TSHR (0.58) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL2002022 0.84 ALDH1A1 (0.67) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL30038050 0.84 ALDH1A1 (0.67) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL28851890 0.84 GAA (0.67) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL19839956 0.83 ALDH1A1 (0.52) TSHRALDH1A1GAANFKB1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4143151-B1 METHOD FOR PRODUCING ESTERS OF HOMOVANILLIC ACID SYMRISE AG (DE) 2025-12-10 EP disclosed
CN-115697961-B Preparation method of homovanillic acid ester 西姆莱斯有限公司 2025-03-18 CN disclosed