SCHEMBL31432939

SCHEMBL31432939

CCCCC(=O)N1Cc2ccc(Br)cc2C1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 1/20 0.54
▸ DPP9 Q86TI2 1/20 0.54
▸ DPP7 Q9UHL4 1/20 0.54
▸ NAMPT P43490 6/20 0.50
▸ GPR183 P32249 1/20 0.50
▸ ABHD6 Q9BV23 3/20 0.47
▸ L3MBTL3 Q96JM7 1/20 0.42
▸ HSD17B3 P37058 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ HSP90AA1 P07900 1/20 0.41
▸ MTNR1B P49286 1/20 0.40
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30575059 0.81 DPP8 (0.56) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL30297512 0.80 ABHD6 (0.52) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL20617796 0.79 DPP8 (0.51) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL20424518 0.79 DPP8 (0.51) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL30575108 0.78 DPP8 (0.50) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL16101941 0.77 NOTUM (0.60) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL6231359 0.77 DPP8 (0.52) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL31432865 0.76 DPP7 (0.69) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL17560188 0.76 NAMPT (0.58) DPP8DPP9DPP7NAMPTABHD6
SCHEMBL31463256 0.75 DPP7 (0.57) DPP8DPP9DPP7NAMPTABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088073-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-05-01 — — WO disclosed
EP-4545138-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-04-30 — — EP disclosed
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