SCHEMBL31433007

SCHEMBL31433007

COc1cc2c(cc1OC)C(=O)N(c1ccccc1)CC2

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
POLB P06746 1/20 0.49
UGCG Q16739 2/20 0.49
HPGD P15428 2/20 0.48
MAPK1 P28482 2/20 0.48
S1PR2 O95136 1/20 0.48
PDE10A Q9Y233 1/20 0.47
PARP1 P09874 1/20 0.46
GPR84 Q9NQS5 3/20 0.46
AOC3 Q16853 2/20 0.46
PDE4D Q08499 1/20 0.46
ACHE P22303 1/20 0.46
TSHR P16473 2/20 0.45
PDE4A P27815 2/20 0.45
JAK2 O60674 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28454320 0.83 PDE10A (0.47) MEN1KMT2AKDM4EALDH1A1POLB
SCHEMBL12870758 0.82 AOC3 (0.58) KDM4EALDH1A1HPGDPARP1GPR84
SCHEMBL31134765 0.77 GRM5 (0.60) MEN1KMT2AKDM4EGPR84PDE4D
SCHEMBL12559547 0.77 NPC1 (0.51) MEN1KMT2AKDM4EALDH1A1MAPK1
SCHEMBL15120583 0.77 MEN1 (0.50) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL11923834 0.75 MEN1 (1.00) MEN1KMT2AKDM4EALDH1A1POLB
SCHEMBL30883376 0.75 MEN1 (1.00) MEN1KMT2AKDM4EALDH1A1POLB
SCHEMBL29420232 0.75 NPC1 (0.68) MEN1KMT2AALDH1A1AOC3SMN1; SMN2
SCHEMBL2600444 0.75 NPC1 (0.68) MEN1KMT2AALDH1A1AOC3SMN1; SMN2
SCHEMBL23364322 0.74 MEN1 (0.49) MEN1KMT2AKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119633858-A Near infrared light mediated heterogeneous composite photocatalyst and preparation method and application thereof 浙江工业大学台州研究院 2025-03-18 CN disclosed