SCHEMBL29420232

SCHEMBL29420232

O=C1c2ccccc2CCN1c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.68
RAB9A P51151 5/20 0.68
BCAT2 O15382 2/20 0.68
PKM P14618 4/20 0.51
GAA P10253 2/20 0.50
TLR9 Q9NR96 1/20 0.50
DDB1 Q16531 1/20 0.49
CRBN Q96SW2 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
CYP11B2 P19099 2/20 0.47
AOC3 Q16853 2/20 0.47
CYP11B1 P15538 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
TP53 P04637 2/20 0.46
LMNA P02545 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
PGR P06401 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2600444 1.00 NPC1 (0.68) NPC1RAB9ABCAT2PKMGAA
SCHEMBL29163639 0.86 BCAT2 (0.65) NPC1RAB9ABCAT2PKMGAA
SCHEMBL31134807 0.86 BCAT2 (0.65) NPC1RAB9ABCAT2PKMGAA
SCHEMBL29500361 0.86 NPC1 (0.71) NPC1RAB9ABCAT2PKMGAA
SCHEMBL26705002 0.86 BCAT2 (0.61) NPC1RAB9ABCAT2PKMKMT2A
SCHEMBL29420242 0.86 BCAT2 (0.65) NPC1RAB9ABCAT2PKMGAA
SCHEMBL15779129 0.84 CASP6 (0.57) NPC1RAB9ABCAT2KMT2AMEN1
SCHEMBL4116681 0.82 BCAT2 (0.53) NPC1RAB9ABCAT2PKMGAA
SCHEMBL3894991 0.82 BCAT2 (0.60) NPC1RAB9ABCAT2PKMGAA
SCHEMBL4116684 0.82 BCAT2 (0.53) NPC1RAB9ABCAT2PKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119633858-A Near infrared light mediated heterogeneous composite photocatalyst and preparation method and application thereof 浙江工业大学台州研究院 2025-03-18 CN disclosed
CN-118580187-A Preparation of dihydroisoquinoline method for preparing norone compounds 四川轻化工大学 2024-09-03 CN disclosed
CN-116813456-A Method for synthesizing cyclic carbonyl compounds from benzylidene compounds 华东理工大学 2023-09-29 CN disclosed
CN-114163385-A Method for promoting tetrahydroisoquinoline compounds to be oxidized into lactam compounds by using surfactant 新乡市润宇新材料科技有限公司 2022-03-11 CN disclosed